Progress on the cell-surface markers and signaling pathways of colorectal cancer stem cells / 基础医学与临床
Basic & Clinical Medicine
;
(12): 133-137, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-509079
ABSTRACT
Colorectal stem cells have many bio-markers, including Lgr5 which expression is associated with THE stage of disease , also regulating the cell cycle , anothers is +4 stem cell , which is associated with tumor heteroge-neity, also expressed Bmi1, arresting cell cycle.Besides there is Msi1.Many studies show that those markers are highly expressed in colorectal cancer , which activate Notch and Wnt signaling pathway , and can promote the pro-gress of tumor .
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Basic & Clinical Medicine
Year:
2017
Type:
Article
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