Human protein tyrosine phosphataseβand its inhibitors:research advances / 国际药学研究杂志
Journal of International Pharmaceutical Research
;
(6): 1049-1053, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-509091
ABSTRACT
Human protein tyrosine phosphataseβ(HPTPβ)is an endothelial cell-specific receptor protein tyrosine phospha?tase(PTP). HPTPβplays an important role in regulating pathophysiological processes such as angiogenesis and cell-to-cell adherens junction,and is taken as a novel target for developing new antiatherosclerosis and antitumor drugs. In this review,the latest research progress in the structure,physiological functions and small molecular inhibitors of HPTPβis summarized.
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of International Pharmaceutical Research
Year:
2016
Type:
Article
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