Research progress of puerarin's antitumor mechanism / 中国综合临床

ABSTRACT

Puerarin is a kind of isoflavone compounds extracted from Chinese herbal medicine radix puerariae,and have antitumor effect which can significantly inhibit lung,stomach,colon cancer,liver cancer,lymphoma cell growth and induce its apoptosis.Related studies had shown that it play a role in anti-tumor mainly by blocking the cell cycle,inducing apoptosis,interventing mitochondrial regulation,injuring mitochondrial cells,and influencing tumor apoptosis signaling pathways et al.