Clinical Observation of Vitamine C Tablets for Local Use in the Treatment of Oral Ulcer after Grinding / 中国药房
China Pharmacy
;
(12): 1123-1125, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-510079
ABSTRACT
OBJECTIVE:
To observe the clinical efficacy and safety of Vitamin C tablets after grinding for local use in the treatment of oral ulcer.METHODS:
Two hundved and eighty-six cases of oral ulcer in our hospital during Feb.2014-Fed.2016 were selected and divided into treatment group and control group according to random number tabel,with 143 cases in each group.Control group was given Guilin watermellon frost,2-3 times a day;treatment group was given Vitamin C tablets powder for local use,2-3 times a day.Clinical efficacy,the time of ulcer disappearance,the incidence of ADR,recurrence rate of ulcer,treatment satisfactory degree were observed in 2 groups.RESULTS:
Total response rate of treatment group was 96.5 %,which was significantly higher than 80.4% of control group,with statistical significance (P<0.05).The time of ulcer disappearance was (2.37 ± 0.89) d in treatment group,which was significantly shorter than (4.12 ± 1.33) d of control group;recurrence rate of ulcer was 3.5%,which was significantly lower than 8.4% of control group;treatment satisfactory degree was 90.9%,which was significantly higher than 79.7% of control group,with statistical significance (P<0.05).There was no statistical significance in the incidence of ADR between 2 groups (P>0.05).CONCLUSIONS:
Vitamin C tablets after grinding for local use has obvious effect on oral ulcer,significantly shortens the time of ulcer disappearance,reduces recurrence rate,and improves treatment satisfactory degree with good safety.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2017
Type:
Article
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