Correlation among heart structure, cardiac function and premature ventricular systole of different ;loads / 心血管康复医学杂志

ABSTRACT

Objective:To explore correlation among heart structure , cardiac function and premature ventricular systo‐le (PVS) of different loads ,.Methods:A total of 220 PVS patients treated in our hospital were selected .According to PVS number‐to‐24h total heart rate ratio ,they were divided into low load group (20% ,n=62) .Another 68 subjects without PVS were regarded as normal control group .Cardiac function indexes and serum level of N terminal pro brain natriuretic peptide (NT‐proBNP) were measured in all groups ,and their correlation was analyzed .Results:Compared with normal control group ,there were significant rise in QT interval ,QRS wave duration and corrected QT interval in medium and high load groups , P<0.05 or <0.01. Compared with normal control group ,there were significant rise in left atrial di‐ameter ( LAD ) , left ventricularoutflow tract dimension ( LVOT ) , left ventricular end‐diastolic dimension (LVEDd) ,right ventricular end‐diastolic dimension (RVEDd) ,left ventricular end‐diastolic volume (LVEDV) , stroke volume (SV) ,left ventricular mass index (LVMI) and NT‐proBNP level ,and significant reduction in left ventricular ejection fraction (LVEF) in medium and high load group ,P<0.05 or <0.01. Bivariate linear correla‐tion analysis indicated that PVS load was significant linear positively correlated with QRS wave duration ,corrected QT interval ,LVEDd ,RVEDd and NT‐proBNP level (r=0.42~0.65 ,P<0.01 all);and significant linear inverse‐ly correlated with LVEF (r= -0.62 ,P=0.001) .Conclusion:Changes may occur in left ventricular structure and function along with PVS load rises .Therefore ,attention should be paid on monitoring related indexes in order to perform early intervention .