Analysis of 575 cases of gastric cardia pathological changes in Chaoshan gastric cardia cancer high risk area / 中国基层医药

ABSTRACT

Objective To observe the clinical features of 575 patients with cardiac diseases from the First Affiliated Hospital of Shantou University Medical College,and to get a preliminary understanding of the incidence of cardia cancer in high incidence area of Chaoshan cardia lesions.Methods Recorded the clinical data of the patients with pathological changes of gastric cardia diagnosed in the First Affiliated Hospital of Shantou University Medical College from 2007 to 2011.Analyzed the distributions of these patients by sex,age and pathological changes.Results There were 575 cases with all kinds of pathological changes of gastric cardia enrolled in this hospital,including 16.34% of chronic inflammation,3.3% of low grade intraepithelial neoplasia,2.26% of high grade intraepithelial neoplasia and 78.09% of gastric cardia cancer.Most patients were gastric cardia cancer.Trend χ2 test results showed that the numbers of gastric cardia cancer patients increased with age(P =0.000).The prevalence of pathological changes of gastric cardia in males was obviously higher than that in females.In gastric cardia cancer the ratio of male to female was 4.76∶1.Conclusion Most of the patients with gastric cardia pathological changes admitted in the First Affiliated Hospital of Shantou University Medical College are middle -aged and elderly men,and gastric cardia cancer is common with a higher frequency in males than that in females.