Value of Intravoxel Incoherent Motion Model of MRI in Differentiating Benign from Malignant Breast Lesions / 中国医学影像学杂志

ABSTRACT

Purpose To investigate the diagnostic value of parameters derived from intravoxel incoherent motion (IVIM) model for benign and malignant breast lesions,and to provide reference for the identification of breast lesions.Materials and Methods 27 cases with 28 benign breast lesions and 34 cases with 35 malignant breast lesions were collected and analyzed retrospectively.All of the patients were examined with IVIM-DWI scans.GE AW 4.4 workstation was used to calculate the value of ADC,D,D* and f.The diagnostic performance of different parameters was evaluated by receiver operating characteristic curve (ROC curve).The ADC,D,D* and f value of malignant group and the benign group were compared,respectively.Results The value of ADC and D were significantly lower in malignant group than in benign group (P＜0.05),and the value of D* and fwere significantly higher in malignant group than in benign group (P＜0.05).The cutoff value of D was 0.74× 10-3 mm2/s,and the AUC were 0.907,the specificity,sensitivity in the diagnosis of malignant breast lesions was 0.86,0.95,respectively.Conclusions Parameters of IVIM-DWI are helpful in the differential diagnosis of benign and malignant breast lesions.