The relationship between genetic polymorphisms of key enzymes in folate metabolism and nonsyndromic cleft of lip with or without palate / 医学研究生学报
Journal of Medical Postgraduates
;
(12): 310-314, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-511383
ABSTRACT
Nonsyndromic cleft of lip with or without palate ( NSCL/P ) is one of the most common congenital birth defects in the maxillofacial region and it is related to genetic factors and environment .Folic acid deficiency , metabolic disorder and the genetic polymorphisms of key metabolic enzymes may be the important factors contributing to NSCL /P .Maternal folic acid intake may reduce the risk of non syndrome cleft lip and palate .This article will review the relationship among the metabolism of folic acid , the genetic polymorphisms of key enzymes in folate metabolism and NSCL /P .
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Medical Postgraduates
Year:
2017
Type:
Article
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