Effect of sciatic nerve block anesthesia combined with spinal epidural anesthesia on vital signs of knee joint replacement surgery / 中国生化药物杂志

ABSTRACT

Objective To investigate the effects of sciatic nerve combined with anesthesia and lumbar spinal combined anesthesia on the vital signs of knee replacement surgery.Methods 112 cases of knee joint replacement surgery with different anesthesia,in The second people's Hospital of Quzhou from August 2013 to August 2015,were selected and randomly divided into experimental group one and experimental group two,56 cases in each group.Experimental group one was treated with sciatic nerve combined with anesthesia,and experimental group two underwent combined spinal-epidural anesthesia,comparison of changes in vital signs,blood pressure and other vital signs after 2 groups.Results After anesthesia,the changes of vital signs such as heart rate and blood pressure of experimental group one was significantly higher than that of experimental group two,the difference was statistically significant(P<0.05).The incidence of adverse events in the experimental group one was significantly lower than that in the experimental group two(26.8％),the difference was statistically significant(P<0.05).The MMSE score in the experimental group one(26.44±0.76)was significantly lower than that of the experimental group two(27.18±0.72),the difference was statistically significant(P<0.05).However,there was no significant difference in MMSE score between the two groups before anesthesia,6 hours,24 hours and 72 hours after operation.Conclusion Patients with knee replacement surgery were treated with sciatic nerve combined with anesthesia after treatment to stabilize the vital signs of patients,and less adverse reactions,more suitable for knee replacement surgery anesthesia treatment.