Analysis of risk factors of postmyocardial infarction syndrome in female patients with acute coronary syndromes / 中国基层医药

ABSTRACT

Objective To analyze the risk factors of postmyocardial infarction syndrome(PMIS)to female patients with acute coronary syndromes(ACS).Methods 258 female patients with ACS complicated with myocardial infarction were selected, of whom 24 patients with PMIS.The clinical data of the two groups were compared and made Logistic regression analysis with different factors to get independent risk factors for PMIS.Results Of 258 female patients with ACS complicated with myocardial infarction, 24 patients with PMIS, the proportion was 9.30%.The age, infarct size, fibrinogen(FIB) level, creatine kinase isoenzymes(CK-MB) level and troponin I(cTnI) level of PMIS group were (64.95±4.95)years old,(11.65±1.52)cm, (2,6.91±1.86)g/L,(36.91±2.46)ng/L,(8.91±1.54)ng/L,respectively, which were higher than those in non-PMIS group[(56.18±4.83)years old,(8.83±1.49)cm2,(5.41±1.58)g/L,(33.88±2.25)ng/L,(6.40±1.17)ng/L](t=8.452,8.814,4.354,6.229,9.695,all P＜0.05).The proportion of patients with smoking and drinking habits, proportion of patients with underlying diseases, proportion of patients with chronic pulmonary disease, proportion of patients with heart and stalk history, proportion of patients with Killip grade Ⅲ-Ⅳ were 16.67%,37.50%,20.83%,66.67%,66.67%,respectively,which were higher than those in non-PMIS group (4.70%,11.97%,8.97%,31.20%,31.20%, x2=5.692,11.553,4.378,12.120,7.172,all P＜0.05).Logistic regression analysis showed that basic disease, history of myocardial infarction, infarct size, Killip classification, CK-MB level and cTnI level were independent risk factors for PMIS.Conclusion The combination of basic disease, history of myocardial infarction, larger infarct size, higher Killip classification, high CK-MB level and high cTnI level can increase the risk of PMIS in female patients with ACS.