Roles of microglia in cerebral ischemia / 国际脑血管病杂志
International Journal of Cerebrovascular Diseases
;
(12): 91-94, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-513293
ABSTRACT
Microglia play a crucial role in inflammation after cerebral ischemia.A large number of studies have shown that microglia are highly plastic cells that can assume different phenotypes and functions in response to specific microenvironmental signals.Microglia can be polarized into the classically activated proinflammatory M1 phenotype or the alternatively activated anti-inflammatory M2 phenotype,and play different roles in ischemic injury.Irnhibiting M1 while stimulating M2 may be a new approach for the treatment of ischemic stroke.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Cerebrovascular Diseases
Year:
2017
Type:
Article
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