Effects of Application Timing of Carboporst Tromethamine on Postpartum Hemorrhage and Hemodynam-ics of Cesarean Section Women with Central Placenta Previa / 中国药房
China Pharmacy
;
(12): 1535-1537, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-513474
ABSTRACT
OBJECTIVE:
To investigate the effects of application timing of carboporst tromethamine on postpartum hemor-rhage and hemodynamics of cesarean section women with centralplacenta previa.METHODS:
Totally 138 parturient women with central placenta previa selected from our hospital during Jan.-Dec. 2015 were divided into observation group and control group ac-cording to random number table,with 69 cases in each group. Both groups received cesarean section. Control group was given Car-boporst tromethamine injection 250 μg on uterine body after the delivery of placenta. Observation group was given Carboporst tro-methamine injection 250 μg on corpora uteri immediately after umbilical cord cutting. The operation duration,intraoperative and postoperative blood loss were observed in 2 groups. The preoperative and postoperative 24 h hemodynamic index,coagulation func-tion and corpora uteri were compared between 2 groups.RESULTS:
The operation duration of observation group was significantly shorter than control group;intraoperative blood loss and 24h blood loss of observation group were significantly less than control group,with statistical significance(P0.05). 24 h after surgery,SBP,DBP,MAP,FIB and D-D of 2 groups were decreased significantly,while HR of them were increased significantly;the observation group was significantly better than the control group,with statistical significance (P0.05).CONCLUSIONS:
Carboporst tromethamine after omphalotomy via uterine body helps to shorten the operation time,reduce intraoperative blood loss,maintain hemodynamic indexes stable and improve coagulation func-tion of cesarean section women with central placenta previa ,with good safety.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2017
Type:
Article
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