Facial basal cell carcinoma: the relationship between clinicopathologic analysis and safety surgical margin / 临床与实验病理学杂志
Chinese Journal of Clinical and Experimental Pathology
;
(12): 68-72, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-513495
ABSTRACT
Purpose To study clinical pathological characteristics,margin status and its influencing factors in different type of facial basal cell carcinoma (BCC).Methods The histopathological features,margin status of the first frozen section and influencing factors was retrospectively analyzed,with review of the relevant literature.The primary outcome variable was the rate of initially positive frozen section margins.Multivariable Logistic regression was used to study histologic subtype,surgical margins,tumor size,location and other factors influence on the rate of initially positive frozen section margins.Results The pathological subtype is the major risk factor,the infiltrative (OR =4.463,95% CI =1.919-10.380,P <0.05) and morpheaform (OR=5.018,95%CI=2.025-16.623,P<0.05) had higher risk on positive surgical margin compared with the nodular.The rate of initially positive frozen section margins of nodular and superficial BCC at different margins were observed but the difference were not significant (P > 0.05).Conclusion The pathological subtype is the major risk factor.Surgical excision with a 3 mm margin can achieve ideal results for nodular and superficial BCC in facial area.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Clinical and Experimental Pathology
Year:
2017
Type:
Article
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