Reproductive factors for ovarian cancer in southern Chinese women / 부인종양
Journal of Gynecologic Oncology
;
: 135-140, 2013.
Article
in English
| WPRIM
| ID: wpr-51357
ABSTRACT
OBJECTIVE:
To investigate the association between reproductive factors and the risk of ovarian cancer among southern Chinese women.METHODS:
A hospital-based case-control study was undertaken in Guangzhou, Guangdong Province, between 2006 and 2008. A structured questionnaire was used to obtain information on parity, oral contraceptive use and other reproductive factors in a sample of 500 incident ovarian cancer patients and 500 controls (mean age, 59 years). Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using unconditional logistic regression models.RESULTS:
High parity was inversely associated with ovarian cancer, with an adjusted OR 0.43 (95% CI, 0.30 to 0.62) for women who had given birth to 3 or more children compared to women who had given no more than one birth. Ever use of oral contraceptives was also protective against ovarian cancer; adjusted OR 0.56 (95% CI, 0.40 to 0.78). No association was found for hormone replacement therapy, menopausal status, hysterectomy and family history of ovarian and/or breast cancer.CONCLUSION:
High parity and oral contraceptive use are associated with a lower risk of ovarian cancer in southern Chinese women.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Ovarian Neoplasms
/
Parity
/
Breast
/
Case-Control Studies
/
Logistic Models
/
Odds Ratio
/
China
/
Surveys and Questionnaires
/
Contraceptives, Oral
/
Hormone Replacement Therapy
Type of study:
Etiology study
/
Observational study
/
Prognostic study
/
Qualitative research
/
Risk factors
Limits:
Child
/
Female
/
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Journal of Gynecologic Oncology
Year:
2013
Type:
Article
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