sIgA of intestinalmucosal barrier in its relevant diseases / 国际儿科学杂志

ABSTRACT

Intestinal mucosal barrier can prevent harmful substance into other tissue,organ and blood across intestinal mucous,and sIgA in feces is an important part of intestinal mucosal barrier.sIgA plays a critical role as an immunological barrier and matters to maintain intestinal homeostasis.SIgA can enhance mucosal barrier[1],protect microbial pathogen from invading and relieve intestinal infammafion symptoms.This review summarizes the research of sIgA in some diseases,to understand its function in the diseases and provide evidence for diagnosis and treatment.