Median effective concentration of lidocaine for obturator nerve block guided by nerve stimulator in patients undergoing transurethral resection of bladder tumor / 中华麻醉学杂志
Chinese Journal of Anesthesiology
; (12): 1480-1483, 2016.
Article
in Zh
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| ID: wpr-514258
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ABSTRACT
Objective To determine the median effective concentration (EC50) of lidocaine for obturator nerve block (ONB) guided by a nerve stimulator in patients undergoing transurethral resection of bladder tumor (TURBT).Methods American Society of Anesthesiologists physical status Ⅰ or Ⅱ patients with bladder tumor,scheduled for elective TURBT,required ONB according to the results of cystoscopy or CT examination performed before operation,with body mass index of 19-30 kg/m2,aged 18-64 yr,were enrolled in the study.ONB was performed with lidocaine using the suprainguinal approach under the guidance of a nerve stimulator.The concentration of lidocaine was determined by up-and-down sequential trial.The initial concentration of lidocaine was 1.5%,and the ratio between the two successive concentrations was 1.2.Successful ONB was considered to be positive response.The EC50 and 95% confidence interval of lidocaine for ONB guided by a nerve stimulator was calculated.Results The EC50 of lidocaine was 0.57%,and the 95% confidence interval was 0.55%-0.59% when used for ONB guided by a nerve stimulator.Conclusion The EC50 of lidocaine is 0.57% when used for ONB guided by a nerve stimulator in the patients undergoing TURBT.
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WPRIM
Language:
Zh
Journal:
Chinese Journal of Anesthesiology
Year:
2016
Type:
Article