Novel intervention target for white matter injury-neurovascular unit / 国际儿科学杂志

ABSTRACT

Perinatal cerebral white matter injury is the most common form of brain injury in premature infants which can lead to developmental disorders of the neurological system,even long-term neurological sequala.The pathogenesis of white matter injury is complicated,and until now there is no effective intervention option.In recent years,as the structural and functional integer of the nervous system,neurovascular unit has attracted much attention in the neuroscience field.The constituents of neurovascular unit and their interaction in the white matter,as well as the progress in the pathophysiology,prevention and treatment of white matter injury are reviewed in this paper.