Clinical studies of Maren capsule and walking exercise as intervention for senile habitual constipation / 国际中医中药杂志

ABSTRACT

Objective To observe the effect of Maren capsule with walking exercise for the patients with senile habitual constipation in community. Methods A total of 112 patients were randomly divided into three groups (control group A and the intervention group B,C). All the three groups took Maren capsule, and group A did not do the walking exercise, group B and C, walked for 30 min and 60 min after dinner, respectively. Two weeks were one course of treatment, all the groups took two courses. Results After treatment, the constipation symptoms and signs scores (4.1 ± 2.0, 4.8 ± 2.1 vs. 5.3 ± 1.5, F=3.886) in the group B and C were significantly lower than those in the control group A (P<0.05) ); and the scores in the group C was lower than that in the group B (P=0.041). Two weeks after the treatment, total effective rates were 36.8%(14/38), 63.2% (24/38), and 77.8% (28/36) in group A, B, C; and the difference was statistically significant (χ2=12.741, P=0.005). Four weeks later, total effective rates were 47.4%(18/38), 76.3%(29/38), 86.1%(31/36) in group A, B, C; and the difference was statistically significant (χ2=13.103, P=0.005). In the following 2 weeks after the end of treatment, total effective rates were 23.7% (9/38), 60.6% (23/38), 75.0% (27/36) in group A, B, C; and the difference was statistically significant (χ2=12.904, P=0.015). Conclusions The Maren capsule with 60 min walking exersice showed significant effect for the senile habitual constipation.