Clinical effect of combination of salbutamol and budesonide in bronchial asthma / 中国生化药物杂志

ABSTRACT

Objective To explore the combination clinical effects of salbutamol and budesonide on bronchial asthma .Methods 120 patients withbronchial asthma in First People's Hospital of Yuhang District were selected and randomly divided into two groups of control group and experimental group with 60 cases in each group.Patients in the control group was treated monotherapy with salbutamol, patients in the experimental group were given albuterol and budesonide combination therapy.The treatment effect on symptoms and lung function of the two groups were compared after two weeks . Results After treatment, the breathing, wheezing sound, gasp and cough remission time were significantly shorter in the experimental group than in the control group,the difference was statistically significant ( P <0.05 ) .The effective rate of the control group was 78.33%, the effective rate of the experimental group was 95.00%,the difference was statistically significant(P<0.05).The improvement of lung function in the experimental group was significantly higher than that in the control group,the difference was statistically significant(P<0.05).Conclusion Compared with monotherapy, the combination of salbutamol and budesonide can improve the efficacy of bronchial asthma patients and improve the quality of life of patients .