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Expression of Platelet-neutrophil Aggregates in Patients With ST-segment Elevation Myocardial Infarction / 中国循环杂志
Chinese Circulation Journal ; (12): 145-148, 2017.
Article in Chinese | WPRIM | ID: wpr-514612
ABSTRACT

Objective:

This work studied platelet-neutrophil aggregates (PNA) expression in patients with acute ST-segment elevation myocardial infarction (STEMI).

Methods:

Our research included in 2 groups STEMI group, n=40 patients admitted in our hospital and Control group, n=30 normal subjects. Blood levels of PNA, platelet-monocyte aggregates (PMA) and platelet-lymphocyte aggregates (PlyA) were measured by lfow cytometry at admission and the results were compared between 2 groups.

Results:

Compared with Control group, STEMI group had similar blood levels of PlyA and PMA,P=0.245 andP=0.312; while increased blood level of PNA,P<0.05. Correlation analysis showed that platelet-leukocyte aggregates (PLA) level was positively related to CK-MB (r=0.4992,P<0.01) and cTnI (r=0.4365,P<0.01).

Conclusion:

Blood level of PLA, especially PNA was significantly higher in STEMI patients which suggested that increased PNA might be sued as a new index for AMI diagnosis in clinical practice.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Circulation Journal Year: 2017 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Circulation Journal Year: 2017 Type: Article