Role of Microglia in Damage after Ischemic Stroke (review) / 中国康复理论与实践
Chinese Journal of Rehabilitation Theory and Practice
;
(12): 42-45, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-514775
ABSTRACT
Microglial cells are the resident immune cells of brain. The activated microglia produces a range of deleterious substances, which plays an important role in the inflammation of post-stroke, such as superoxide, nitric oxide, matrix metalloproteinases, etc. The activa-tion of microglia may involve triggering receptor expressed on myeloid cells-1, Toll-like receptors 4, peroxisome proliferator-activated re-ceptors, purinergic receptors, etc. Intervention targeted to microglial receptor is becoming a new strategy for ischemic stroke.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Rehabilitation Theory and Practice
Year:
2017
Type:
Article
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