Study progress of Tacrolimus treatment on steroid-resistant nephrotic syndrome in children / 中华实用儿科临床杂志
Chinese Journal of Applied Clinical Pediatrics
;
(24): 392-395, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-514832
ABSTRACT
Steroid-resistant nephrotic syndrome (SRNS) is a relatively difficult clinical type of treatment.The major therapy measures in present include steroid and immunosuppressant.Commonly used immunosuppressant include tacrolimus,cyclosporin,cyclophosphamide,mycophenolate mofetil,ect.Tacrolimus-induced clinical remission rate is superior to other immunosuppressive agents,has been the first-line agent of SRNS.Because of the individual difference in metabolism,the drug concentration of tacrolimus should be determined periodically.In order to obtain optimal efficacy of tacrolimus and reduce renal toxicity,the treatment protocols of small doses with long courses for children with SRNS were recommended.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Practice guideline
Language:
Chinese
Journal:
Chinese Journal of Applied Clinical Pediatrics
Year:
2017
Type:
Article
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