Study on Improving the Quality Standard of Gubi Zhitong Liquor / 中国药房
China Pharmacy
;
(12): 1249-1253, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-514980
ABSTRACT
OBJECTIVE:
To improve the quality standard for Guibi zhitong liquor.METHODS:
TLC was used for the qualita-tive identification of Radix angelicae,Notopterygium incisum,Radix aucklandiae and Magnolia officinalis in the preparation;HPLC was used for the contents determination of imperatorin and cinnamaldehydethe column was Waters Symmetry Shield RP-C18 with mobile phase of methanol-water for imperatorin(6040,V/V)and methanol-water for cinnamaldehyde(3565,V/V)at a flow rate of 1.0 mL/min,detection wavelength was 254 nm for imperatorin and 290 nm for cinnamaldehyde,column temperature was 25℃,and the injection volume was 20μL.RESULTS:
The TLC spots of R. angelicae,N. incisum,R. aucklandiae and M. of-ficinalis were clear and well separated,negative control without interference. The linear range was 3.0-30.0 μg/mL for imperatorin (r=0.9998)and 3.978-39.78 μg/mL for cinnamaldehyde(r=0.9999);RSDs of precision,stability and reproducibility tests were lower than 2.0%;recoveries were 96.94%-102.64%(RSD=2.37%,n=6)and 96.78%-99.53%(RSD=1.00%,n=6). CONCLU-SIONSThe improved standard more effectively control the quality of the Guibi zhitong liquor.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Qualitative research
Language:
Chinese
Journal:
China Pharmacy
Year:
2017
Type:
Article
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