A study on effects of sodium selenite, hyaluronidase and anisodamine on infarction size and left ventricular myocardial contractility and relaxation in rat with myocardial infarction / 中国病理生理杂志
Chinese Journal of Pathophysiology
;
(12)1986.
Article
in Chinese
| WPRIM
| ID: wpr-515585
ABSTRACT
The present study compared effects of sodium selenite(Se), hyaluronidase (Hy) and anisodamine(An) on infarction size(IS), left ventricular myocardial contractility (LVMC) and relaxation(LVMR) on the third day after the ligation of left coronary artery in rats. The results showed that Se, with the dose of 30?g/kg/day either before or after the ligation, has a same effect on reducing IS as Hy and An. However, Se, at the same time, can significantly improve LVMC and LVMR, which were evalued by indexes of LVSP, ?dp/dtmax and T value, while Hy and An can not. It is suggested that Se is superior to Hy and An when they are used in treatment of acute myocardial infarction.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Pathophysiology
Year:
1986
Type:
Article
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