The inhibition of electric acupuncture on milk-induced fever and the relation to the contents of central cAMP and LEK in rabbits / 中国病理生理杂志

ABSTRACT

Intravenous injection of milk in dose of 0.6ml/kg into rabbits produced fever, putting an acupuncture needle into "Baihui (Hundred Flower) point" and gave intermittent electric stimulations. The thermal response peak (△T) of fever fell, the thermal response index (TRI) reduced and body temperature recovered fast from fever. The evidence showed that electric acupuncture can inhibit this type of fever. The contents of cAMP and L-enkephalin (LEK) in cerebrospinal fluid before fever, at the intervals of 2 and 3.5 hours in fever were determined by radioimmunoassay (RIA), and the resuIts indicated the central concentrations of cAMP in fever increased significantly, as well as the central concentrations of LEK increased at interval of 2 hours, but recovered at interval of 3.5 hours. While electric acupuncture inhibited fever of rabbits, it reduced central concentrations of cAMP and increased the central concentrations of LEK. The results suggested the role of electric acupuncture on the type of fever may associate with the changes of the concentrations of these central substances.