Observation on fever response of leukocytic pyrogen fever and change of cAMP content in cerebrospinal fluid during electric needling "Baihui" point in febrile rabbits / 中国病理生理杂志

ABSTRACT

In order to analyze the mechanism of febrifugal effect of electric needling "Baihui (Hundreds Converge)" point of febrile rabbits, 108 rabbits were divided into 5 groups, serveing as experimental animals. The results obtained showed 1. In febrile rabbits induced by monoeytic pyrogen, electric needling "Bai hui" points has significant febrifugal effect, i. e. inhibiting the rise of body temperature, in the meantime the cAMP content rose in c. s. f. was markedly inhibited. 2. On febrile rabbits, electric needling blocking "Bai hui" point and Non-acupoint exhibited no marked febrifugal effect, i. e. showing apparently fever response, and at the same time cAMP contents in c. s. f. was strikingly increased. 3. Blocking of "Bai hui" point itself did not produce any effect on pyrogen-induced fever and cAMP content increased.The author inferred that the mechanism of inhibitory effect of electric needling "Bai hui" points in febrile rabbits might be closele assocated with feeling of local sensible tissue (e. g. free nerve endings) in "Bai hui" point, and with producing nerve impuls which transmitted through some mode to brain. As a result, increased cAMP was inhibited and setpoint to move up was inhibited.