Changes of the plasma and tissue lipidperoxidant levels in rats with experimental acute pancreatitis / 中国病理生理杂志

ABSTRACT

Acute necro-hemorrhagic pancreatitis (ANHP) was induced in rats by intra-pancreatic duct injection with a mixed solution of bile salt and trypsin. After 6- to 30-hr of operation the increase of plasma lipidperoxidant (LPO) levels from 4.67 to 20.5 nmol/ml and the fall of plasma amylase levels from 6577 to 2629 U were observed in the rats with ANHP. The values of the plasma LPO at 10-,20-,and 30-hr in the rats with ANHP were significantly higher than those in the control (P