The effects of sodium selenite on the AOH-induced DNA single strand breaks and lipid peroxidation / 中国病理生理杂志
Chinese Journal of Pathophysiology
;
(12)1986.
Article
in Chinese
| WPRIM
| ID: wpr-516070
ABSTRACT
The alkaline elution and flurometric DNA assay for the mesurement of the DNA single-strand breaks (SSB) and the thiobarbituric, acid test for the mesurement of molondialdehyde (MDA) were adopted in this article to study the effects of sodium selenite (Na_2SeO_3) on the mutagenicity of AOH. The results showed that pretreating the cells or epithelia with 10~(-5) or 10~(-6)M Na_2SeO_3 for 4 hours prior to exposure to AOH could inhibit the AOH-induced DNA SSB and the content of MDA which was the terminal pro duct of the lipid peroxidation (comparing with the control group, P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Pathophysiology
Year:
1986
Type:
Article
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