Effects of trimetazidine on reperfusion arrhythmias and its mechanism / 中华麻醉学杂志
Chinese Journal of Anesthesiology
;
(12)1994.
Article
in Chinese
| WPRIM
| ID: wpr-516290
ABSTRACT
The experiment of recirculating blood perfusion device showed that trimetazidine (TMZ ) 30 mol/L could significantly inhibit the arrhythmias induced by ischemia and reperfusion, decrease the content of malondialdehyde and improve superoxide dismutase activity of red blood cell in isolated rabbit hearts. In the experiment with coronary artery occlusion of rats, TMZ 4mg/kg administered intravenously could also inhibit arrhythmias induced by ischemia and reperfusion. The mechanism may be related to the depression of lipid peroxidation reaction.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Anesthesiology
Year:
1994
Type:
Article
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