Double-equilibration technique for measuring liquid/gas partition coefficients of isoflurane / 中华麻醉学杂志
Chinese Journal of Anesthesiology
; (12)1995.
Article
in Zh
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| ID: wpr-516539
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ABSTRACT
This study was designed to establish methods to measure partition coefficients of inhaled anesthetics at 1 atmosphere and 37 C by using syringe-flask double equilibration technique. Olive oil/gas (O/G), saline/gas (S/G), and water/gas (W/G) partition coefficients of isoflurane were 90.20?2.01, 0.6256?0.109, and 0. 741?0.025, respectively. Even though O/G was 150 folds of S/G,coefficients of variation for both O/G and S/G were less than 3%. The results indicate that the established double-equilibration technique has a very high repeatability and is applicable to wide ranges of inhaled anesthetics' solubilities.
Full text:
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Index:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Anesthesiology
Year:
1995
Type:
Article