The effect of partial liquid ventilation on the ultrastructure of pulmonary surfactant system in endotoxin-induced acute lung injury in rats / 中国病理生理杂志
Chinese Journal of Pathophysiology
;
(12)2000.
Article
in Chinese
| WPRIM
| ID: wpr-517107
ABSTRACT
AIM:
To study the effect of partial liquid ventilation on the ultrastructure of pulmonary surfactant(PS) system in endotoxin-induced acute lung injuryMETHODS:
The effect of partial liquid ventilation on the ultrastructure of PS system in endotoxin-induced acute lung injury was observed with electronmicroscope histochemistry.RESULTS:
There was ultrastructure impairment of PS system in endotoxin-induced acute lung injury, the pulmonary surfactant layer was discontinuous, lamellar bodies and plasmosomes in type Ⅱ pneumonocytes vacuolated, and a few of them were even necrotized and disrupted into the alveolar space. The pulmonary surfactant layer was still continuous, the vacuolation of lamellar bodies and plasmosomes in type Ⅱ pneumonocytes was little with partial liquid ventilation.CONCLUSION:
Partial liquid ventilation can lessen the impairment of PS system in endotoxin-induced acute lung injury in rats.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Pathophysiology
Year:
2000
Type:
Article
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