Changes of the contraction and relaxation of thoracic aortae in rats with chronic sinoaortic denervation / 中国病理生理杂志
Chinese Journal of Pathophysiology
;
(12)2000.
Article
in Chinese
| WPRIM
| ID: wpr-517116
ABSTRACT
AIM:
To investigate long-term effects of sinoaortic denervation (SAD) on the contraction and relaxation of thoracic aortae in rats.METHODS:
SD rats underwent either SAD or sham operation at the age of 10 weeks. At 4,8, 16, and 32 weeks after operation, the contraction and relaxation of the thoracic aortae were measured by isolated artery technique.RESULTS:
The NE-induced contraction and ACh-induced relaxation of aortic rings were progressively increased and depressed respectively after SAD.CONCLUSION:
Vascular functional changes induced by purely blood pressure variability is similar to those observed in well-established experimental hypertensive states.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Pathophysiology
Year:
2000
Type:
Article
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