Preoperative endoscopic cryotherapy plus surgery for esophageal cancer / 中华消化内镜杂志

ABSTRACT

Objective Wether preoperative freezing plus traditional operative resection would improve 5 year survival of patient with esophageal cancer was studied. Methods 50 patients admitted for esophageal cancer were divided equally at random.The treatment group (n=25) received cryotherapy before traditional surgery.The rest,without pretreatment,had surgery as controls.Their 1,3,5 year survival rates were contrasted. Results With pretreatment the 1,3,5 year survival rate reached 92,76,56 percent respectively,while that of the controls attained 80,40,and 28 percent accordingly.Statistically significant difference in survival did exist between groups by the end of 3 and 5 years after the combined therapy, yet no difference was detected within 1 year. Conclusion Preoperative cryotherapy could reduce the possibility of lymphatic metastasis,iatrogenic spread during operation and improve patient’ s immunological functions and life span.