Paraneoplastic Pemphigus: A Report of Two Cases / 中华皮肤科杂志
Chinese Journal of Dermatology
; (12)1994.
Article
in Zh
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| ID: wpr-517397
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ABSTRACT
Paraneoplastic pemphigus(PNP) is a clinically, histologically, and immunopathologically distinct autoimmune bullous disease characterized by severe painful mucosal erosions and polymorphous skin lesions. Histopathology shows acantholysis with lichenoid dermatitis or keratinocyte necrosis, and there are autoantibodies to various epidermal proteins with underlying neoplasia. We report two cases of paraneoplastic pemphigus in China firstly. The clinical, histologic, and immunopathologic findings of both cases strongly suggest the diagnosis of paraneoplastic pemphigus associated with Castleman′ s tumor.
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Language:
Zh
Journal:
Chinese Journal of Dermatology
Year:
1994
Type:
Article