A clinical study on effects of propofol or isoflurane anesthesia on sodium nitroprusside-induced hypotension / 中华麻醉学杂志
Chinese Journal of Anesthesiology
;
(12)1995.
Article
in Chinese
| WPRIM
| ID: wpr-517458
ABSTRACT
Objective To investigate the effect of propofol anesthesia on hemodynamic changes and dose requirement of sodium nitroprusside (SNP) during SNP-induced hypotension.Methods Sixteen patients undergoing elective microneurosurgery were randomly assigned to one of two groups propofol group and isoflurane group. In propofol group (n=8) anesthesia was maintained with propofol (infusion rate 100?g?kg -1?min -1 ) after dural opening, whereas in isoflurane group (n=8) anesthesia was maintained with 1.3 MAC isoflurane.After 20 min the MAP of both groups was reduced by 40% with continuous infusion of 0.01% SNP solution.Results Blood pressure was more easily reduced and maintained in propofol group, and was lower in propofol group than that in isoflurane group following SNP withdrawl (P
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Anesthesiology
Year:
1995
Type:
Article
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