Clinical Significance of Determining TXB_2、PAgT、6-Keto-PGF_(1?) in Plasma of Lung Carcinoma Patients / 中国医师杂志

ABSTRACT

Objective To explore the clinical significance of determining the levels of plasma TXB 2,PAgT,6-Keto-PGF 1? in the lung carcinoma patients.Methods The levels of plasma TXB 2,PAgT and 6-Keto-PGF 1? were determined in 43 patients with lung carcinoma and 45 healthy controls,and 36 cases of 43 patients with lung carcinoma were randomly divided into two groups(A) conventional treatment plus warfarin sodium,(B) conventional treatment without anticoagulant.We also determined the level of plasma Fib in both group A and group B,besides examined the levels of plasma TXB 2,PAgT and 6-Keto-PGF 1? before and after treatment.Results Statistical analysis showed that the levels of TXB 2 and PAgT were significantly higher,but the levels of 6-Keto-PGF 1? was significantly lower in the patients with lung carcinoma than those in healthy controls(P0 05).Conclusion The determination of plasma TXB 2,PAgT and 6-Keto-PGF 1? for lung carcinoma patients are helpful in diagnosis and treatment of lung carcinoma.