Anti-thrombotic,Choleretic and Anti-ulcerous Actions of Rhizoma Ligustici / 中国药房

ABSTRACT

OBJECTIVE:To study the anti-thrombotic,choleretic and anti-ulcerous actions of Rhizoma Ligustici METHO_DSExperiments were carried out on conventional models of choleresis and ulceration,and on a thrombotic model of using direct current continuously to stimulate the unilateral carotid artery of anesthetic rat RESULTS:Alcoholic extract of Rhizoma Ligustici 3g herb/kg and 10g herb/kg id or ig,increased choleresis and prolonged the time for arterial thrombosis induced by electric stimulation in rats,but did not prolonged coagulative time,PT and KPTT The extract 5g herb/kg and 15g herb/kg ig,inhibited the formation of gastric ulcers induced by water immersion,stress,HCl and indomethacin-alcohol in mice CONCLU_SIONRhizoma Ligustici has anti-thrombotic choleretic and anti-ulcerous actions