Effects of Serum of Mice Treated With Ruixiang Langdu(Stellera chamaejasme L.) abstract on Proliferation and Clonal Formation of K562 Cells / 中国药房
China Pharmacy
;
(12)2001.
Article
in Chinese
| WPRIM
| ID: wpr-517873
ABSTRACT
OBJECTIVE:
To study the antitumor mechanism of Ruixiang Langdu(Stellera chamaejasme L ) abstracts(SCA)METHODS:
SCA-contained serum was derived from mice pre-administrated with different oral dosages of SCA and at different times after administration The effects of the serum on the proliferation of K562 leukemic cells were observed with MTT assay and clone formationRESULTS:
After mixing with the SCA-contained serum derived at 1,2,4,8h after giving SCA(3,6 and 12g/kg),the rates of MTT transformation and clone formation of K562 cells were decreased significantly The SCA-contained serum 12 h after giving drug was more effective than othersCONCLUSION:
The SCA-contained serum inhibited the proliferation of tumor cells,which may be one of its important antitumor mechanism
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2001
Type:
Article
Similar
MEDLINE
...
LILACS
LIS