Use of mycobacterium vaccae as immuno-stimulant in the preparation of H.influenzae type b (Hib) antisera
Journal of Preventive Medicine
;
: 66-70, 2004.
Article
in Vietnamese
| WPRIM
| ID: wpr-5179
ABSTRACT
In order to enhance the capability of antiserum production rabbits, Mycobacterium vaccae was used to stimulate rabbit’s immune system unspecifically before immunization with Haemophilus influenzae type b (Hib). The results showed that only single immunization with Hib antigen the number of rabbits had response fulfill depended-time requirements (harvested after 1 or 6 months) varied from 30% to 70%, harvesting time for antiserum with fulfilled quantity and quality was 24 weeks (6 months) (2 courses induced immunization). Stimulating rabbit’s immune system by M. vaccae, then inducing rabbit’s immunization with Hib antigen the number of rabbits had response fulfiling requirements varied from 71.4% to 100%; harvesting time for antiserum with fulfilled quantity and quality was 5 weeks (only after 1 course induced immunization). Sensitivity and specificity of antiserum were unchanged
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Adjuvants, Immunologic
/
Helicobacter pylori
/
Immune Sera
/
Mycobacterium
Language:
Vietnamese
Journal:
Journal of Preventive Medicine
Year:
2004
Type:
Article
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