Inhibitory effect of canstatin RNA transfection on the growth of cultured rabbit vascular smooth muscle cells / 中国病理生理杂志
Chinese Journal of Pathophysiology
;
(12)2000.
Article
in Chinese
| WPRIM
| ID: wpr-518004
ABSTRACT
AIM:
To investigate the effect of canstatin on cultured rabbit vascular smooth muscle cells(VSMC).METHODS:
By means of cationic liposome mediated method, canstatin RNA was transferred into cultured VSMC. The proliferation quantity of VSMC were determined by the cell counting method and thymidine(-TdR) incorporation.RESULTS:
Canstatin RNA could be effectively transferred into cultured primary rabbit aortic smooth muscle cells by the cationic liposome-Dosper and could markedly inhibit VSMC proliferation.CONCLUSION:
Transfection of canstatin RNA could inhibit the growth of VSMC in vitro.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Pathophysiology
Year:
2000
Type:
Article
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