Effect of intestinal endotoxemia on hepatic energy metabolism in acute liver failure / 中国病理生理杂志
Chinese Journal of Pathophysiology
;
(12)1999.
Article
in Chinese
| WPRIM
| ID: wpr-518120
ABSTRACT
AIM:
To study the effect of intestinal endotoxemia(IETM) on hepatic energy metabolism in acute liver failure.METHODS:
Intoxication by thioacetamide (TAA) was used to establish rat model of acute liver injury.Ketone body(acetoacetate and ?-hydroxybutyrate) in arterial blood and ATP content of hepatocellular mitochondria were determined by using enzymatic fluorimetric micromethod.Colectomy was adopted in observing the changes in plasma endotoxin content and serum alanine aminotransferase (ALT) activity.RESULTS:
In the TAA group,plasma endotoxin content and serum ALT activity were all significantly higher than those in the control group(P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Pathophysiology
Year:
1999
Type:
Article
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