Study on the Influence of Arsenic Trioxide on the Expressions of Gastric Cancer Cell Metastasis Associated Genes / 中国药房
China Pharmacy
;
(12)2001.
Article
in Chinese
| WPRIM
| ID: wpr-518308
ABSTRACT
OBJECTIVE:
To detect the expressions of five gastric cancer cell metastasis associated genes induced by arsenic trioxideMETHODS:
The expressions of CD44,P53,nm23,H-ras,PCNA induced by arsenic trioxide were examined by immunohistochemistry methodRESULTS:
Arsenic trioxide induced the decrease of the expressions of CD44,P53,PCNA in gastric cancer cells;the expressions of nm23 and H-ras were not changed by As2 O 3CONCLUSION:
It is tentatively proved that the antineoplastic action of As2 O 3 may be related to the down-regulation of CD44,P53 and PCNA
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2001
Type:
Article
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