Effects of angiotensin converting enzyme inhibitor on the arterial elastase after balloon injury / 中国病理生理杂志
Chinese Journal of Pathophysiology
;
(12)2000.
Article
in Chinese
| WPRIM
| ID: wpr-518474
ABSTRACT
AIM:
To study the effects of angiotensin converting enzyme inhibitor(ACEI) on elastase after balloon injury.METHODS:
The carotid arteries and aortas twelve-weeks-old Wistar male rats were injured by balloon catheter. The rats were divided into experimental and control groups in which ACEI (temocapril-HCl,10 mg?kg -1 ?d -1 ) and the vehicle were administered 2 days before injury respectively and the animals were sacrificed on day 2, 3, 5 and 10, respectively. In situ hybridization, immunohistochemistry and elastase activity bioassay were used for studying elastase .RESULTS:
The intimal area on day 10 in the experimental group was significantly suppressed compared to that in the control rats( P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Pathophysiology
Year:
2000
Type:
Article
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