Determination of the Content of Ciprofloxacin Lactate in Eye Drops by Dual-wavelength Spectrophotometry / 中国药房

ABSTRACT

OBJECTIVE:Dual-wavelength spectrophotometry was developed for the determination of ciprofloxacin lactate in its eye drops.METHODS:Detection was performed at wavelength 237nm and 279nm with 0.1mol/L HCl as diluent.RESU_LTSThe assay was linear for ciprofloxacin lactate in the concentration range of 3～9?g/ml,r=0.9 998;The mean recovery was 101.6%,RSD was 2.16%.CONCLUSION:This method is simple,quick,accurate and suitable for the determination of ciprofloxacin lactate in its eye drops.