Determination of the Content of Ofloxacin in Compound Ofloxacin Eye Drops by RP-HPLC / 中国药房
China Pharmacy
;
(12)1991.
Article
in Chinese
| WPRIM
| ID: wpr-518626
ABSTRACT
OBJECTIVE:
To establish a RP-HPLC method to determine the content of ofloxacin in compound ofloxacin eye dropsMETHODS:
Using Shim-pack ODS as fixed phase,a mixture to citric acid(0 05mol/L)-acetonitrile-ammonium acetate(0 5mol/L)-0 3% phosphoric acid(78∶22∶1∶3)as mobile phase,and detecting wavelength293nm,flow rate1 0ml/minRESULTS:
The linear range of ofloxacin was 8 12?g~40 6?g(r=0 9 996,n=5) The average recovery was 99 29% and RSD(n=6)was 0 57%CONCLUSION:
The method is rapid,simple and accurate
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
1991
Type:
Article
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