Cost-effectiveness Analysis of Three Preventing Schemes for Cisplatin-induced Vomiting / 中国药房

ABSTRACT

OBJECTIVE:To discuss the economic effects of different therapeutic schemes in the treatment of the same illness.METHODS:202 cases receiving cisplatin chemotherapy were randomly divided into three groups according to the preventing schemes receivedgroup Ⅰ,sulpiride;groupⅡ,ondansetron;groupⅢ,metoclopramide.Data was evaluated using pharmacoeconomic cost-effectiveness analysis.RESULTS:The effective rate of sulpiride was 87.1%,expense of one therapeutic course being 93.30 yuans and increase of 1% effective rate costed 1.07 yuans.The effective rate of ondansetron was 93.5%,expense of one therapeutic course being 448.26 yuans and increase of 1% effective rate costed 4.79 yuans.The effective rate of metoclopramide was 57.5%,expense of one therapeutic course being 54.33 yuans and increase of 1% effective rate costed 0.94 yuans.CONCLUSION:The sulpiride scheme is the most rational one.