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Effects of sterigmatocystin on interferon-? secretion of human peripheral blood mononuclear cells in vitro / 中国病理生理杂志
Article in Chinese | WPRIM | ID: wpr-518696
Responsible library: WPRO
ABSTRACT

AIM:

To explore the putative effects of sterigmatocystin (ST) on human help T lymphocyte(Th1)function.

METHODS:

The effects of ST on interferon-?(IFN-?)secretion of human peripheral blood mononuclear cells(HPBMc) in vitro were determined with ELISA method.

RESULTS:

The effects of ST on IFN-? secretion of HPBMc in vitro were closely dependent on ST concentrations. ST at relatively lower concentrations (0.03125-0.12500 mg/L) showed inhibiting effects on IFN-? secretion. While, stimulating effects could be found when ST concentration was above 0.25mg/L. The highest level was seen in ST 1 mg/L group ( P

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Pathophysiology Year: 1986 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Pathophysiology Year: 1986 Type: Article