Study on CsA Therapeutic Window Concentration in Renal Transplant Recipients / 中国药房
China Pharmacy
;
(12)1991.
Article
in Chinese
| WPRIM
| ID: wpr-518911
ABSTRACT
OBJECTIVE:
To establish an optimal therapeutic window concentration of CsA trough levels in renal transplant recipients on triple immunosuppressants regimenMETHODS:
A total 1 874 samples from 268 renal transplant recipients were measured by fluorescence polarization immunoassay(FPIA) According to the duration after operation and clinical diagnoses ,the whole blood CsA trough levels were compared among subgroupsRESULTS:
The optimal therapeutic window concentration of CsA was 300~400?g/L(within 1 month after operation),250~350?g/L(2nd~3rd month),150~250?g/L(4th~6th month),100~200?g/L(7th~12th month)and 100~150?g/L(more than 12 months)CONCLUSION:
The above mentioned therapeutic window concentratin of CsA trough levels was ideal for renal transplant recipients with no marked acute toxic effects and rejection reaction
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
1991
Type:
Article
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