Assessment of optic disc and retinal nerve fiber layer in normal-tension glaucoma and high-tension glaucoma patients / 中华眼底病杂志

ABSTRACT

Purpose To evaluate differences in the pattern of optic disc and retinal nerve fiber layer (RNFL) damage in normal tension glaucoma (NTG) and high tension glaucoma (HTG) patients. Methods We enrolled 49 eyes of 49 patients30 NTG (IOP≤21 mm Hg,1 mm Hg=0.133 kPa), 19 HTG(IOP≥25 mm Hg). Mean age was 59.2?12.3 (range, 36-75) for HTG patients, and 59.6?8.6(range, 39-71) for NTG patients. All patients underwent complete ophthalmic examination, achromatic automated perimetry (AAP), scanning laser ophthalmoscopy (SLO), scanning laser polarimetry (SLP), optical coherence tomography (OCT) and Heidelberg retinal tomography (HRT). All patients had glaucomatous optic nerve damage and abnormal AAP. Results There were no differences in mean deviation on AAP between NTG and HTG eyes ( P =0.37), while the corrected pattern standard deviation was larger in NTG than in HTG eyes ( P =0.014). Cup∶disc area ratios in global ( P =0.03) and three sectors ( P