Biopsy of sentinel lymph nodes in breast cancer / 中国普通外科杂志

ABSTRACT

To summarize the operative technique and the clinical value of sentinel lymph node biopsy (SLNB) in breast cancer,a literature review was made on SLNB. The conclusion is as follows(1)As compared with blue dye or radioactive tracer, combining the two techniques can increase the positive detection rate and decrease the false-negative rate of the sentinel lymph nodes .(2) Pathological examination by serial sectioning, IHC or RT-PCR increases the detection rate of micrometastases, which is helpful for the accurate clinical staging of auxillary lymph nodes. (3)SLNB is a simple procedure with minimal morbidity and highly predictive value of the status of auxillary lymph nodes.It has emerged as a potential substitute for the routine auxillary lymph node dissection.